Estudios

Dermatología

Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017 Jan;128-129:1-7. doi: 10.1016/j.prostaglandins.2016.12.001. Epub 2016 Dec 23.


Sarfaraz Alam M, Ali MS, Zakir F, Alam N, Intakhab Alam M, Ahmad F, Siddiqui MR, Ali MD, Ansari MS, Ahmad S, Ali M. Enhancement of Anti-Dermatitis Potential of Clobetasol Propionate by DHA [Docosahexaenoic Acid] Rich Algal Oil Nanoemulsion Gel. Iran J Pharm Res. 2016 Winter;15(1):35-52. FULL TEXT


Barnadas MA, Díaz Encarnación MM. Refractory Cutaneous IgA Vasculitis Treated with Omega-3 Fatty Acids. Case Rep Dermatol. 2016 Nov 29;8(3):333-340. FULL TEXT


Yoshida S, Yasutomo K, Watanabe T. Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. J Med Invest. 2016;63(3-4):187-91. doi: 10.2152/jmi.63.187. FULL TEXT


Barcelos RC, de Mello-Sampayo C, Antoniazzi CT, Segat HJ, Silva H, Veit JC, Piccolo J, Emanuelli T, Bürger ME, Silva-Lima B, Rodrigues LM. Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. J Dermatol Sci. 2015 Sep;79(3):298-304.


Barcelos RC, de Mello-Sampayo C, Antoniazzi CT, Segat HJ, Silva H, Veit JC, Piccolo J, Emanuelli T, Bürger ME, Silva-Lima B, Rodrigues LM. Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. J Dermatol Sci. 2015 Sep;79(3):298-304.


Haitz KA, Anandasabapathy N. Docosahexaenoic Acid alleviates atopic dermatitis in mice by generating T regulatory cells and m2 macrophages. J Invest Dermatol. 2015 Jun;135(6):1472-4.


Gruber F, Ornelas CM, Karner S, Narzt MS, Nagelreiter IM, Gschwandtner M, Bochkov V, Tschachler E. Nrf2 deficiency causes lipid oxidation, inflammation and matrix-protease expression in DHA supplemented and UVA irradiated skin fibroblasts. Free Radic Biol Med. 2015 May 13. pii: S0891-5849(15)00217-8. doi: 10.1016/j.freeradbiomed.2015.05.006.


Kendall AC, Pilkington SM, Massey KA, Sassano G, Rhodes LE, Nicolaou A.“Distribution of Bioactive Lipid Mediators in Human Skin.”J Invest Dermatol. 2015 Feb 10. doi: 10.1038/jid.2015.41.


McCusker MM, Grant-Kels JM. Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. Clin Dermatol. 2010 Jul-Aug;28(4):440-51.


Kim HH, Cho S, Lee S, Kim KH, Cho KH, Eun HC, Chung JH. Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. J Lipid Res. 2006 May;47(5):921-30. Epub 2006 Feb 7. FULL TEXT


Shahbakhti H, Watson RE, Azurdia RM, Ferreira CZ, Garmyn M, Rhodes LE. Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo. Photochem Photobiol. 2004 Sep-Oct;80(2):231-5.


Ziboh VA, Miller CC, Cho Y. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr. 2000 Jan;71(1 Suppl):361S-6S. FULL TEXT


Okuda Y, Sawada T, Mizutani M, Sone H, Suzuki S, Kawakami Y, Soma M, Suzuki M, Yaoita H, Yamashita K. Restoration of myo-inositol uptake by eicosapentaenoic acid in human skin fibroblasts cultured in high-glucose medium. Life Sci. 1995;57(5):PL71-4.


Brown ER, Subbaiah PV. Differential effects of eicosapentaenoic acid and docosahexaenoic acid on human skin fibroblasts. Lipids. 1994 Dec;29(12):825-9.


Grønn M, Christensen E, Hagve TA, Christophersen BO. The Zellweger syndrome: deficient conversion of docosahexaenoic acid (22:6(n-3)) to eicosapentaenoic acid (20:5(n-3)) and normal delta 4-desaturase activity in cultured skin fibroblasts. Biochim Biophys Acta. 1990 May 22;1044(2):249-54.


Rosenthal MD, Whitehurst MC. Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. J Cell Physiol. 1982 Nov;113(2):298-306.